Quick Answer: Ajovy must be stored in the refrigerator between 2°C and 8°C. When refrigeration is not possible, it can be kept at room temperature for up to 7 days not exceeding 30°C.

Like many medicines, storing Ajovy properly is vital to ensure its safety and effectiveness. Unlike most medications, however, Ajovy requires refrigeration and has a limited shelf life when kept at room temperature.

Here are some handy tips to keep your migraine injections in top condition, whether you’re at home, spending the day out, or travelling!
4AllFamily UK - Travel Cooling Cases for Medications like Ajovy

What is Ajovy?

Ajovy is a prescription medication commonly used in the UK and designed to prevent migraines in adults. Its active ingredient, fremanezumab, is a calcitonin gene-related peptide (CGRP) inhibitor. It works similarly to Aimovig and Emgality by blocking CGRP, a molecule involved in triggering migraines.

Ajovy is administered via subcutaneous injection (under the skin), typically once a month or once every three months, depending on your prescription. It is a preventive treatment aimed at reducing the frequency and severity of migraines rather than treating them during an attack.

Available in both prefilled syringes and autoinjector pens, Ajovy is only available by prescription and should always be used under the guidance of your GP or healthcare provider.

Related article: How Long Can Aimovig Be Out of The Fridge Without Deteriorating?

Ajovy Storage Instructions and Temperature

Fremanezumab, the active ingredient in your Ajovy injections, is temperature-sensitive, so storing Ajovy correctly is crucial to maintain its effectiveness. Incorrect storage could result in reduced effectiveness of your chronic migraine treatment.

According to Medicines.org.uk:

  • Ajovy must be refrigerated at temperatures between 2°C and 8°C until it is ready for use.
  • If refrigeration isn’t available, your Ajovy pens or syringes can be kept at room temperature (not exceeding 30°C) for up to seven days.
  • Ajovy should never be frozen, exposed to direct light, or shaken, as these conditions can damage the medication.
  • Once Ajovy has been removed from refrigeration, it should not be put back in the fridge.

Related article: How Long Can Emgality Be Unrefrigerated?

What Happens If Ajovy Isn’t Refrigerated?

If Ajovy is left unrefrigerated for too long, its potency and safety may be compromised. This could make the medication less effective and disrupt your migraine prevention plan. The active ingredient deteriorates quickly when exposed to improper temperatures.

Ajovy can tolerate short periods outside refrigeration, such as when being transported from the pharmacy to your home. However, any exposure beyond the recommended conditions may render the medication unsafe to use. Always follow the storage instructions included with your medication, and consult your GP or pharmacist if you have concerns.

How Long Does Ajovy Last in the Fridge?

When stored properly in a refrigerator, Ajovy lasts until the expiry date printed on the packaging. This is typically around one year from the purchase date. Never use medication that has expired, even if it appears fine.

Dispose of expired syringes or pens safely, following your local disposal guidelines. In the UK, unused medicines can often be returned to your pharmacy for safe disposal.

How Long Can Ajovy Be Out of the Fridge?

As noted, you can leave Ajovy out of the fridge for up to seven days if needed. However, it should not be exposed to temperatures higher than 30°C during this time.

If a syringe or pen has been out of the fridge for longer than seven days, or if it has been exposed to temperatures above 30°C, do not use it. Instead, safely dispose of it and use a fresh one from the fridge.

How Can You Tell if Ajovy Has Gone Bad?

Ajovy is a clear, colourless liquid. If the liquid appears cloudy, discoloured, or contains particles, it may have gone bad. Do not use it and contact your pharmacist for further advice.

How to Travel with Ajovy Pens & Syringes

Ajovy’s storage requirements can make travelling a bit tricky, particularly when heading to warm destinations or travelling for extended periods. However, with proper planning, you can protect your medication from spoiling.

Whether you’re holidaying in Europe, exploring the British countryside, or travelling on another continent, it’s essential to keep Ajovy cool while travelling.

  • If you’re travelling for more than seven days, you'll need to carry your syringes in a refrigerated travel case.
  • If you're travelling for less than 7 days but heading somewhere with temperatures above 30°C, you’ll need a reliable travel cooling case.

4AllFamily’s medical-grade travel coolers, finally available in the UK, are an excellent choice. Designed for transporting refrigerated and temperature-sensitive medications, they help keep your Ajovy injections cool. 

For shorter trips where you only need to keep Ajovy protected from the heat (below 30°C), consider the Companion Medical Cool Bag or the Chillers cooling Pouches. They keep your injections at a safe room-temperature for several hours or even days!

For longer trips where your injections need to stay refrigerated during travel, consider the Voyager Mini Travel Fridge, the Explorer 3-in-1 Travel Cooler, or the Nomad Refrigerated Travel Cases. 

For more travel cooling options, explore our catalogue or contact our support team.

Additional Tips for Keeping Ajovy Cool on the Go!

  • Plan ahead: If you’re due an injection during your trip, speak to your GP or pharmacist beforehand to ensure you have everything you need, including extra medication in case of delays or unexpected events.
  • Pack your supplies: Don’t forget alcohol wipes, a travel sharps container, and anything else required for your injections. 
  • Bring documentation: Carry a copy of your prescription or a doctor’s note explaining the need for your medication. This can help at airport security or border checks, particularly if flying abroad. When flying within the UK, you do not need any documentation to bring Ajovy on a plane. 

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January 08, 2025

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The information presented in this article and its comment section is for informational purposes only and is not intended as a replacement for professional medical advice. Always consult with a qualified healthcare provider for any medical concerns or questions you may have.