Quick Answer: Humira (Adalimumab) must be refrigerated between 2°C and 8°C before use and can be stored at room temperature, always below 25°C, for up to 14 days.
Humira, or Adalimumab, is a vital medication used by over 1.4 million people worldwide to manage inflammation-related conditions like rheumatoid arthritis and Crohn’s disease. This injectable drug can help alleviate discomfort and improve quality of life for those with autoimmune disorders.
Whether you use the pre-filled Humira pens or syringes, proper storage is essential to ensure the medication remains safe and effective.
Before first use, Humira must be refrigerated between 2°C and 8°C. After opening, it can be stored at room temperature below 25°C for up to 14 days. If stored improperly, the medication can degrade, losing its potency and potentially becoming unsafe.
Let’s break down everything you need to know about Humira storage, answering key questions such as:
- Why does Humira need to be refrigerated?
- How long does it last in the fridge?
- How long can it be left out?
- What happens if it gets too warm?
- Can Humira freeze?
- How can you keep Humira cool while travelling?
Related article: 4AllFamily Humira Travel Case: Make Travelling Easier!
Prefer a quick summary? Watch the video at the end of this article!
Why Does Humira Need to Be Refrigerated?
Humira is a biologic medicine containing adalimumab, a protein-based substance designed to block tumour necrosis factor (TNF). By targeting TNF, Humira helps reduce inflammation in autoimmune conditions such as rheumatoid arthritis and Crohn’s disease.
As a biologic, Humira’s active ingredient is highly sensitive to changes in temperature and exposure to light.
Keeping it refrigerated between 2°C and 8°C ensures the medication remains stable and effective throughout its shelf life. The manufacturer, AbbVie, has established these guidelines based on extensive testing to guarantee Humira’s therapeutic effectiveness.
What Happens If Humira Is Not Refrigerated?
Humira can be stored at room temperature below 25°C for up to 14 days without losing its effectiveness. However, exposure to higher temperatures or direct sunlight may cause the active ingredient to degrade, reducing the medication’s efficacy and impacting treatment outcomes.
Incorrect storage can also lead to contamination, potentially posing health risks. If you suspect that Humira has been stored improperly, it’s best not to use it. Always consult your healthcare provider for guidance in such cases.
Related article: What Happens If Enbrel Is Left Unrefrigerated?
How Long Does Humira Last?
When kept in the fridge at 2°C to 8°C and protected from light in its original packaging, Humira remains effective until the expiry date printed on the pen or syringe.
Once removed from refrigeration, it must be used within 14 days and should not be returned to the fridge after being stored at room temperature.
Can Humira Freeze?
No, Humira must not be frozen. Freezing irreversibly damages the medication, rendering it ineffective and unsafe.
To prevent freezing, store Humira away from the freezer compartment of your fridge, and avoid leaving it in extremely cold environments for extended periods.
When travelling to cold climates, keep Humira close to your body or use a cooler with anti-freeze technology, such as those from 4AllFamily.
Storing Humira at Room Temperature
If storing Humira at room temperature, ensure the environment remains below 25°C. Follow these tips for safe storage:
- Use a cooler if temperatures exceed 25°C.
- Keep Humira away from direct sunlight.
- Do not leave Humira in a parked car, as temperatures can rise quickly.
- Avoid placing Humira near heat sources such as ovens or radiators.
What to Do If Humira Gets Warm
If Humira is exposed to temperatures above 25°C, even briefly, it may lose its effectiveness.
Signs of heat damage include cloudiness, discolouration, or visible particles in the solution. However, these signs may not always be noticeable. When in doubt, dispose of the medication and consult your healthcare provider for advice.
Video: How to Store Humira
Prefer watching instead of reading? Check out the video below for a quick overview of how to store Humira safely, whether you’re at home or travelling.
We’d Love to Hear Your Thoughts!
Have questions or tips about storing Humira? Share your experiences in the comments below to help others keep their medication safe and effective!
